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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DNM2 All Species: 19.39
Human Site: S302 Identified Species: 47.41
UniProt: P50570 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.33
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P50570 NP_001005360.1 870 98064 S302 A L R S K L Q S Q L L S L E K
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001103119 870 98099 S302 A L R S K L Q S Q L L S L E K
Dog Lupus familis XP_542065 865 97464 S302 A L R S K L Q S Q L L S L E K
Cat Felis silvestris
Mouse Mus musculus P39054 870 98127 S302 T L R S K L Q S Q L L S L E K
Rat Rattus norvegicus P39052 870 98212 S302 T L R S K L Q S Q L L S L E K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q7SXN5 691 77244 P176 I L K Y I S N P N S I I L A V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P27619 877 97791 K297 G L R D K L Q K Q M L T L E K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P39055 830 93389 K304 T L R D S L Q K K M F A M E K
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8LFT2 780 86625 R267 Q E D I L M N R S I K D A L V
Baker's Yeast Sacchar. cerevisiae P54861 757 84953 T244 K R T I G V I T K L D L M D S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 99.7 95.1 N.A. 98.1 98 N.A. N.A. N.A. N.A. 32.9 N.A. 64.4 N.A. 61.9 N.A.
Protein Similarity: 100 N.A. 100 97.2 N.A. 99 99.1 N.A. N.A. N.A. N.A. 51 N.A. 76.9 N.A. 76.5 N.A.
P-Site Identity: 100 N.A. 100 100 N.A. 93.3 93.3 N.A. N.A. N.A. N.A. 13.3 N.A. 66.6 N.A. 40 N.A.
P-Site Similarity: 100 N.A. 100 100 N.A. 93.3 93.3 N.A. N.A. N.A. N.A. 26.6 N.A. 80 N.A. 66.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 35.5 35.6 N.A.
Protein Similarity: N.A. N.A. N.A. 52.5 54.1 N.A.
P-Site Identity: N.A. N.A. N.A. 0 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 30 0 0 0 0 0 0 0 0 0 0 10 10 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 10 20 0 0 0 0 0 0 10 10 0 10 0 % D
% Glu: 0 10 0 0 0 0 0 0 0 0 0 0 0 70 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % F
% Gly: 10 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 0 0 20 10 0 10 0 0 10 10 10 0 0 0 % I
% Lys: 10 0 10 0 60 0 0 20 20 0 10 0 0 0 70 % K
% Leu: 0 80 0 0 10 70 0 0 0 60 60 10 70 10 0 % L
% Met: 0 0 0 0 0 10 0 0 0 20 0 0 20 0 0 % M
% Asn: 0 0 0 0 0 0 20 0 10 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % P
% Gln: 10 0 0 0 0 0 70 0 60 0 0 0 0 0 0 % Q
% Arg: 0 10 70 0 0 0 0 10 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 50 10 10 0 50 10 10 0 50 0 0 10 % S
% Thr: 30 0 10 0 0 0 0 10 0 0 0 10 0 0 0 % T
% Val: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 20 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _